Anorectal syndromes
- Anorectal symptoms such as anal pain, discharge, bleeding, ulceration, altered bowel habit and tenesmus can be due to a sexually transmitted infection (STI). STIs should therefore be excluded as part of the evaluation
- Risk is highest in men who have sex with men (MSM)
- Where there is a high suspicion that anorectal symptoms are STI-related, cases should ideally be managed by a specialist sexual health service
- This guideline provides advice for those who work in areas with limited access to specialist sexual health services, or where the patient is reluctant to attend such a service. Discussion with a sexual health physician is recommended in all cases
Proctitis
- Inflammation of the rectum (i.e. distal 10-12 cm)
- Can be associated with anal pain, discharge and tenesmus
- Sexually acquired proctitis occurs predominantly in people who participate in receptive anal intercourse
- Non-infectious causes also possible, e.g. ulcerative colitis
Proctocolitis
- Inflammation of the colonic mucosa and rectum
- Associated with symptoms of proctitis, diarrhoea and abdominal cramps
- Sexually acquired proctocolitis can be acquired by receptive anal intercourse or oral-anal contact, depending on pathogen
- Sexually acquired proctitis
- Herpes simplex viruses (HSV Types 1 and 2)
- Chlamydia trachomatis, particularly strains that cause lymphogranuloma venereum (LGV)
- Neisseria gonorrhoeae
- Treponema pallidum (syphilis)
- Mycoplasma genitalium
- Sexually aquired proctocolitis
- LGV
- Shigella
- Campylobacter
- Entamoeba histolytica
Symptoms |
Comments/Considerations |
Anal discharge |
|
Anal pain |
Often accompanied by spasm. May preclude proctoscopy |
Perianal ulcers and systemic features |
|
Altered bowel habit |
Constipation predominates in proctitis. Alternating constipation and diarrhoea occurs in proctocolitis |
Tenesmus |
Sensation of needing to pass stool indicates inflammation of anal canal |
- Anorectal symptoms in people with a history of anal sex
- NB It is important to take a sexual history in people with anorectal symptoms, as sexual practices may not otherwise be disclosed
- Patients should ideally be referred to a specialist sexual health service, as management may be complex, and further testing may be required
- If referral is not possible, discussion with a sexual health physician is recommended
- The patient should be examined, and tests should be clinician-collected. Ideally this should be done via proctoscope
Investigations
- STI screening as per sexual health check guideline
- In addition, rectal culture swab for Neisseria gonorrhoeae (if available)
- Rectal herpes swab
- Request LGV if rectal chlamydia positive. This must be discussed with a sexual health physician or microbiologist
- If diarrhoea, faecal specimen for bacterial pathogens
Syndromic treatment of non-specific proctitis |
|
Note: 21-day course of doxycycline to cover the possibility of LGV, which requires a long course of treatment
- If specific STI tests are negative, corresponding treatment for the pathogen can be ceased
- LGV testing is not routinely offered in the community and MUST be discussed with a sexual health physician or microbiologist
- If all tests are negative, cease medications and seek specialist advice if symptoms persist
- Advise to abstain from sex or use condoms until treatment complete and symptoms resolved, and until partner(s) tested and treated (if indicated)
- Contact tracing is important to prevent re-infection and reduce transmission
- All sexual contacts in the last 3 months should be notified
- Most patients choose to tell contacts themselves; giving written information can be helpful
- Notifying all contacts may not be possible e.g. if there is insufficient information or a threat of violence
Management of sexual contacts
- Contacts should have a sexual health check, including testing for LGV if index case positive
- Advise contacts to abstain from sex or use condoms until results are available, and treatment (if any) completed
- If index case or contacts test positive for an STI, see appropriate STI guideline for management
- Patient-delivered partner therapy is not legal in Aotearoa New Zealand
Review in 1 week (in person or by phone):
|
Test of cure
|
Retesting
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Referral to or discussion with a sexual health specialist is recommended for:
- Patients with anorectal symptoms and a history of receptive anal sex, where there is a high suspicion that symptoms are STI related
- Screening and treatment of sexual contacts if clinician wishes
- Allergy or contraindication to standard treatment options
- Complicated clinical situations for further management
- 100% of patients with proctitis have been investigated with appropriate tests to exclude STIs